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Zip nucleic acid: a new reliable method to increase the melting temperature of real-time PCR probes

TaqMan genotyping with real-time PCR is a reliable method for single nucleotide polymorphism detection, which is done by probes. These oligonucleotides should be short enough to avoid mismatch hybridization, as well as having 5–10°C higher melting temperature than the primers of real-time PCR reacti...

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Detalhes bibliográficos
Main Authors: Alvandi, Ehsan, Koohdani, Fariba
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3922743/
https://ncbi.nlm.nih.gov/pubmed/24495816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2251-6581-13-26
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