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Zip nucleic acids are potent hydrolysis probes for quantitative PCR

Zip nucleic acids (ZNAs) are oligonucleotides conjugated with cationic spermine units that increase affinity for their target. ZNAs were recently shown to enable specific and sensitive reactions when used as primers for polymerase chain reaction (PCR) and reverse-transcription. Here, we report their...

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Autors principals: Paris, Clément, Moreau, Valérie, Deglane, Gaëlle, Voirin, Emilie, Erbacher, Patrick, Lenne-Samuel, Nathalie
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853127/
https://ncbi.nlm.nih.gov/pubmed/20071749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1218
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