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Zip nucleic acids are potent hydrolysis probes for quantitative PCR

Zip nucleic acids (ZNAs) are oligonucleotides conjugated with cationic spermine units that increase affinity for their target. ZNAs were recently shown to enable specific and sensitive reactions when used as primers for polymerase chain reaction (PCR) and reverse-transcription. Here, we report their...

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Main Authors: Paris, Clément, Moreau, Valérie, Deglane, Gaëlle, Voirin, Emilie, Erbacher, Patrick, Lenne-Samuel, Nathalie
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853127/
https://ncbi.nlm.nih.gov/pubmed/20071749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1218
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