Response of primary glioblastoma cells to therapy is patient specific and independent of cancer stem cell phenotype

BACKGROUND: Glioblastoma multiforme (GBM) contains a population of cells that exhibit stem cell phenotypes. These cancer stem cells (CSCs) may be a source of therapeutic resistance, although support for this important concept is limited. METHODS: We determined whether early-passage GBM CSCs respond...

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Bibliografske podrobnosti
Main Authors: Fouse, Shaun D., Nakamura, Jean L., James, C. David, Chang, Susan, Costello, Joseph F.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
Teme:
Basic and Translational Investigations
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3922516/
https://ncbi.nlm.nih.gov/pubmed/24311636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/not223
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