The novel arylindolylmaleimide PDA-66 displays pronounced antiproliferative effects in acute lymphoblastic leukemia cells

BACKGROUND: Prognosis of adult patients suffering from acute lymphoblastic leukemia (ALL) is still unsatisfactory. Targeted therapy via inhibition of deregulated signaling pathways appears to be a promising therapeutic option for the treatment of ALL. Herein, we evaluated the influence of a novel ar...

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Main Authors: Kretzschmar, Christin, Roolf, Catrin, Langhammer, Tina-Susann, Sekora, Anett, Pews-Davtyan, Anahit, Beller, Matthias, Frech, Moritz J, Eisenlöffel, Christian, Rolfs, Arndt, Junghanss, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3922486/
https://ncbi.nlm.nih.gov/pubmed/24502201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-71
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