Angiotensin II rapidly increases phosphatidate-phosphoinositide synthesis and phosphoinositide hydrolysis and mobilizes intracellular calcium in cultured arterial muscle cells.

Smooth muscle cells were cultured from rat thoracic aorta and labeled to a stable specific activity with 45Ca2+, myo-[2-3H]inositol, or 32Pi. The efflux of 45Ca2+ was monitored over 10-sec intervals. Angiotensin II (AII) increased the amount of 45Ca2+ lost by 5-fold in the first 10-sec interval afte...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Smith, J B, Smith, L, Brown, E R, Barnes, D, Sabir, M A, Davis, J S, Farese, R V
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1984
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392242/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6096858/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.24.7812
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