Angiotensin II rapidly increases phosphatidate-phosphoinositide synthesis and phosphoinositide hydrolysis and mobilizes intracellular calcium in cultured arterial muscle cells.

Smooth muscle cells were cultured from rat thoracic aorta and labeled to a stable specific activity with 45Ca2+, myo-[2-3H]inositol, or 32Pi. The efflux of 45Ca2+ was monitored over 10-sec intervals. Angiotensin II (AII) increased the amount of 45Ca2+ lost by 5-fold in the first 10-sec interval afte...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Smith, J B, Smith, L, Brown, E R, Barnes, D, Sabir, M A, Davis, J S, Farese, R V
Format: Artigo
Langue:Inglês
Publié: 1984
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC392242/
https://ncbi.nlm.nih.gov/pubmed/6096858
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