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Exon-Skipping Antisense Oligonucleotides to Correct Missplicing in Neurogenetic Diseases
Alternative splicing is an important regulator of the transcriptome. However, mutations may cause alteration of splicing patterns, which in turn leads to disease. During the past 10 years, exon skipping has been looked upon as a powerful tool for correction of missplicing in disease and progress has...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Mary Ann Liebert, Inc.
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3922311/ https://ncbi.nlm.nih.gov/pubmed/24506781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2013.0461 |
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