Human Aortic Valve Calcification Is Associated With an Osteoblast Phenotype

BACKGROUND: Calcific aortic stenosis is the third most common cardiovascular disease in the United States. We hypothesized that the mechanism for aortic valve calcification is similar to skeletal bone formation and that this process is mediated by an osteoblast-like phenotype. METHODS AND RESULTS: T...

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Главные авторы: Rajamannan, Nalini M., Subramaniam, Malayannan, Rickard, David, Stock, Stuart R., Donovan, Janis, Springett, Margaret, Orszulak, Thomas, Fullerton, David A., Tajik, A.J., Bonow, Robert O., Spelsberg, Thomas
Формат: Artigo
Язык:Inglês
Опубликовано: 2003
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3922288/
https://ncbi.nlm.nih.gov/pubmed/12719282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/01.CIR.0000070591.21548.69
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