Atorvastatin inhibits calcification and enhances nitric oxide synthase production in the hypercholesterolaemic aortic valve

Objective: To study in a rabbit model the expression of endothelial nitric oxide synthase (eNOS) in association with the development of calcification of the aortic valve, and to assess the effects of atorvastatin on eNOS expression, nitrite concentration, and aortic valve calcification. Methods: Rab...

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Detalhes bibliográficos
Main Authors: Rajamannan, N M, Subramaniam, M, Stock, S R, Stone, N J, Springett, M, Ignatiev, K I, McConnell, J P, Singh, R J, Bonow, R O, Spelsberg, T C
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2005 by Heart 2005
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1768932/
https://ncbi.nlm.nih.gov/pubmed/15894785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/hrt.2003.029785
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