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Atrial natriuretic factor elicits an endothelium-independent relaxation and activates particulate guanylate cyclase in vascular smooth muscle.

A 26 amino acid synthetic peptide fragment of atrial natriuretic factor (ANF) relaxed isolated rabbit aortic segments in which the endothelium was either intact or functionally destroyed. The relaxations were temporally associated with increases in levels of cGMP with no change in the levels of cAMP...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Winquist, R J, Faison, E P, Waldman, S A, Schwartz, K, Murad, F, Rapoport, R M
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 1984
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Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392208/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6150486/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.23.7661
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