Atrial natriuretic factor elicits an endothelium-independent relaxation and activates particulate guanylate cyclase in vascular smooth muscle.

A 26 amino acid synthetic peptide fragment of atrial natriuretic factor (ANF) relaxed isolated rabbit aortic segments in which the endothelium was either intact or functionally destroyed. The relaxations were temporally associated with increases in levels of cGMP with no change in the levels of cAMP...

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Hauptverfasser: Winquist, R J, Faison, E P, Waldman, S A, Schwartz, K, Murad, F, Rapoport, R M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1984
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC392208/
https://ncbi.nlm.nih.gov/pubmed/6150486
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