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Overcoming Product Inhibition in Catalysis of the Intramolecular Schmidt Reaction

A method for carrying out the intramolecular Schmidt reaction of alkyl azides and ketones using a substoichiometric amount of catalyst is reported. Following extensive screening, the use of the strong hydrogen bond donating solvent hexafluoro-2-propanol was found to be consistent with low catalyst l...

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Bibliografiska uppgifter
Huvudupphovsmän: Motiwala, Hashim F., Fehl, Charlie, Li, Sze-Wan, Hirt, Erin, Porubsky, Patrick, Aubé, Jeffrey
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3921892/
https://ncbi.nlm.nih.gov/pubmed/23687993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja402848c
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