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Role of a disulfide bridge in the immune function of major histocompatibility class I antigen as studied by in vitro mutagenesis.

Polymorphic major histocompatibility class I antigens have highly conserved disulfide bridges in the second and third external domains. To study the role of a disulfide bridge, we have introduced a mutation into the mouse H-2Ld gene by oligonucleotide-directed site-specific mutagenesis, disrupting t...

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Autors principals: Shiroishi, T, Evans, G A, Appella, E, Ozato, K
Format: Artigo
Idioma:Inglês
Publicat: 1984
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC392183/
https://ncbi.nlm.nih.gov/pubmed/6334311
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