Engineering an intracellular pathway for major histocompatibility complex class II presentation of antigens.

The presentation of antigenic peptides by major histocompatibility complex (MHC) class II molecules to CD4+ T cells is critical to the function of the immune system. In this study, we have utilized the sorting signal of the lysosomal-associated membrane protein LAMP-1 to target a model antigen, huma...

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Detalhes bibliográficos
Main Authors: Wu, T C, Guarnieri, F G, Staveley-O'Carroll, K F, Viscidi, R P, Levitsky, H I, Hedrick, L, Cho, K R, August, J T, Pardoll, D M
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC40464/
https://ncbi.nlm.nih.gov/pubmed/8524826
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