Engineering an intracellular pathway for major histocompatibility complex class II presentation of antigens.

The presentation of antigenic peptides by major histocompatibility complex (MHC) class II molecules to CD4+ T cells is critical to the function of the immune system. In this study, we have utilized the sorting signal of the lysosomal-associated membrane protein LAMP-1 to target a model antigen, huma...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Wu, T C, Guarnieri, F G, Staveley-O'Carroll, K F, Viscidi, R P, Levitsky, H I, Hedrick, L, Cho, K R, August, J T, Pardoll, D M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40464/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8524826/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.25.11671
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