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Role of a disulfide bridge in the immune function of major histocompatibility class I antigen as studied by in vitro mutagenesis.

Polymorphic major histocompatibility class I antigens have highly conserved disulfide bridges in the second and third external domains. To study the role of a disulfide bridge, we have introduced a mutation into the mouse H-2Ld gene by oligonucleotide-directed site-specific mutagenesis, disrupting t...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Shiroishi, T, Evans, G A, Appella, E, Ozato, K
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1984
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392183/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6334311/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.23.7544
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