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Loss of MeCP2 From Forebrain Excitatory Neurons Leads to Cortical Hyperexcitation and Seizures

Mutations of MECP2 cause Rett syndrome (RTT), a neurodevelopmental disorder leading to loss of motor and cognitive functions, impaired social interactions, and seizure at young ages. Defects of neuronal circuit development and function are thought to be responsible for the symptoms of RTT. The major...

詳細記述

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書誌詳細
主要な著者: Zhang, Wen, Peterson, Matthew, Beyer, Barbara, Frankel, Wayne N., Zhang, Zhong-wei
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3921436/
https://ncbi.nlm.nih.gov/pubmed/24523563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4900-12.2014
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