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Jak/Stat Signaling Stimulates Zebrafish Optic Nerve Regeneration and Overcomes the Inhibitory Actions of Socs3 and Sfpq

The regenerative failure of mammalian optic axons is partly mediated by Socs3-dependent inhibition of Jak/Stat signaling (Smith et al., 2009, 2011). Whether Jak/Stat signaling is part of the normal regenerative response observed in animals that exhibit an intrinsic capacity for optic nerve regenerat...

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Detalles Bibliográficos
Main Authors: Elsaeidi, Fairouz, Bemben, Michael A., Zhao, Xiao-Feng, Goldman, Daniel
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3921430/
https://ncbi.nlm.nih.gov/pubmed/24523552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3898-13.2014
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