Upregulation of Leukemia Inhibitory Factor (LIF) during the Early Stage of Optic Nerve Regeneration in Zebrafish

Fish retinal ganglion cells (RGCs) can regenerate their axons after optic nerve injury, whereas mammalian RGCs normally fail to do so. Interleukin 6 (IL-6)-type cytokines are involved in cell differentiation, proliferation, survival, and axon regrowth; thus, they may play a role in the regeneration...

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Autors principals: Ogai, Kazuhiro, Kuwana, Ayaka, Hisano, Suguru, Nagashima, Mikiko, Koriyama, Yoshiki, Sugitani, Kayo, Mawatari, Kazuhiro, Nakashima, Hiroshi, Kato, Satoru
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4146584/
https://ncbi.nlm.nih.gov/pubmed/25162623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106010
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