SOCS3 deletion promotes optic nerve regeneration in vivo

Axon regeneration failure accounts for permanent functional deficits following CNS injury in adult mammals. However, the underlying mechanisms remain elusive. In analyzing axon regeneration in different mutant mouse lines, we discovered that deletion of suppressor of cytokine signaling 3 (SOCS3), in...

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Detalhes bibliográficos
Main Authors: Smith, Patrice D., Sun, Fang, Park, Kevin Kyungsuk, Cai, Bin, Wang, Chen, Kuwako, Kenichiro, Martinez-Carrasco, Irene, Connolly, Lauren, He, Zhigang
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796263/
https://ncbi.nlm.nih.gov/pubmed/20005819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2009.11.021
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