SOCS3 deletion promotes optic nerve regeneration in vivo

Axon regeneration failure accounts for permanent functional deficits following CNS injury in adult mammals. However, the underlying mechanisms remain elusive. In analyzing axon regeneration in different mutant mouse lines, we discovered that deletion of suppressor of cytokine signaling 3 (SOCS3), in...

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Huvudupphovsmän: Smith, Patrice D., Sun, Fang, Park, Kevin Kyungsuk, Cai, Bin, Wang, Chen, Kuwako, Kenichiro, Martinez-Carrasco, Irene, Connolly, Lauren, He, Zhigang
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796263/
https://ncbi.nlm.nih.gov/pubmed/20005819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2009.11.021
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