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Generation of TALEN-Mediated GR(dim) Knock-In Rats by Homologous Recombination
Transcription Activator-Like Effector Nucleases (TALEN) are potential tools for precise genome engineering of laboratory animals. We report the first targeted genomic integration in the rat using TALENs (Transcription Activator-Like Effector Nucleases) by homology-derived recombination (HDR). We ass...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3921256/ https://ncbi.nlm.nih.gov/pubmed/24523878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088146 |
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