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Combined Pharmacological Induction of Hsp70 Suppresses Prion Protein Neurotoxicity in Drosophila
Prion diseases are rare and aggressive neurodegenerative disorders caused by the accumulation of misfolded, toxic conformations of the prion protein (PrP). Therapeutic strategies directed at reducing the levels of PrP offer the best chance of delaying or halting disease progression. The challenge, t...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3921213/ https://ncbi.nlm.nih.gov/pubmed/24523910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088522 |
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