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Heterotropic modulation of selectin affinity by allosteric antibodies affects leukocyte rolling
Selectins are a family of adhesion receptors designed for efficient leukocyte tethering to the endothelium under shear. As a key property to resist premature bond disruption, selectin adhesiveness is enhanced by tensile forces that promote the conversion of a bent into an extended conformation of th...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3921101/ https://ncbi.nlm.nih.gov/pubmed/24431230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302147 |
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