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L- and P-Selectins Collaborate to Support Leukocyte Rolling in Vivo When High-Affinity P-Selectin-P-Selectin Glycoprotein Ligand-1 Interaction Is Inhibited

P-selectin glycoprotein ligand-1 (PSGL-1) binding to P-selectin controls early leukocyte rolling during inflammation. Interestingly, antibodies and pharmacological inhibitors (eg, rPSGL-Ig) that target the N-terminus of PSGL-1 reduce but do not abolish P-selectin-dependent leukocyte rolling in vivo...

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Bibliografski detalji
Glavni autori: Ridger, Victoria C., Hellewell, Paul G., Norman, Keith E.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2005
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602366/
https://ncbi.nlm.nih.gov/pubmed/15743805
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