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Hypoxia induces re-entry of committed cells into pluripotency
Adult stem cells reside in hypoxic niches and embryonic stem cells (ESCs) are derived from a low oxygen environment. However, it is not clear whether hypoxia is critical for stem cell fate since for example human ESCs (hESCs) are able to self-renew in atmospheric oxygen concentrations as well. We no...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3921075/ https://ncbi.nlm.nih.gov/pubmed/23765801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1446 |
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