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Hypoxia induces re-entry of committed cells into pluripotency

Adult stem cells reside in hypoxic niches and embryonic stem cells (ESCs) are derived from a low oxygen environment. However, it is not clear whether hypoxia is critical for stem cell fate since for example human ESCs (hESCs) are able to self-renew in atmospheric oxygen concentrations as well. We no...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Mathieu, Julie, Zhang, Zhan, Nelson, Angelique, Lamba, Deepak A., Reh, Thomas A., Ware, Carol, Ruohola-Baker, Hannele
פורמט: Artigo
שפה:Inglês
יצא לאור: 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3921075/
https://ncbi.nlm.nih.gov/pubmed/23765801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1446
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