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CFTR is the primary known apical glutathione transporter involved in cigarette smoke induced adaptive responses in the lung
One of the most abundant antioxidants in the lung is glutathione (GSH), a low molecular weight thiol, which functions to attenuate both oxidative stress and inflammation. GSH is concentrated in the epithelial lining fluid (ELF) of the lung and can be elevated in response to the increased oxidant bur...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3920665/ https://ncbi.nlm.nih.gov/pubmed/22266045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2012.01.001 |
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