Lateral Clustering of TLR3:dsRNA Signaling Units Revealed by TLR3ecd:3Fabs Quaternary Structure

Toll-like receptor 3 (TLR3) recognizes dsRNA and initiates an innate immune response through the formation of a signaling unit (SU) composed of one double-stranded RNA (dsRNA) and two TLR3 molecules. We report the crystal structure of human TLR3 ectodomain (TLR3ecd) in a quaternary complex with thre...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Luo, Jinquan, Obmolova, Galina, Malia, Thomas J., Wu, Sheng-Jiun, Duffy, Karen E., Marion, James D., Bell, Jessica K., Ge, Peng, Zhou, Z. Hong, Teplyakov, Alexey, Zhao, Yonghong, Lamb, Roberta J., Jordan, Jarrat L., San Mateo, Lani R., Sweet, Raymond W., Gilliland, Gary L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920545/
https://ncbi.nlm.nih.gov/pubmed/22579623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.05.006
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak