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Small Molecule Inhibitors of the TLR3/dsRNA Complex

The protein-RNA interface has been regarded as “undruggable” despite its importance in many biological processes. The toll-like receptor 3 (TLR3)/double-stranded RNA (dsRNA) complex provides an exciting target for a number of infectious diseases and cancers. We describe the development of a series o...

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Detalhes bibliográficos
Main Authors: Cheng, Kui, Wang, Xiaohui, Yin, Hang
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3068529/
https://ncbi.nlm.nih.gov/pubmed/21355588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja111312h
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