Common Chromosomal Fragile Site Gene WWOX in Metabolic Disorders and Tumors

WWOX, a gene that spans the second most common chromosomal fragile site (FRA16D), often exhibits homozygous deletions and translocation breakpoints under multiple cellular stresses induced by extrinsic or intrinsic factors, such as hypoxia, UV, and DNA damage regents. Loss of WWOX is closely related...

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Bibliografiske detaljer
Main Authors: Li, Juan, Liu, Jie, Ren, Yu, Yang, Jin, Liu, Peijun
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2014
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920169/
https://ncbi.nlm.nih.gov/pubmed/24520212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.7727
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