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Common Chromosomal Fragile Site Gene WWOX in Metabolic Disorders and Tumors
WWOX, a gene that spans the second most common chromosomal fragile site (FRA16D), often exhibits homozygous deletions and translocation breakpoints under multiple cellular stresses induced by extrinsic or intrinsic factors, such as hypoxia, UV, and DNA damage regents. Loss of WWOX is closely related...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Ivyspring International Publisher
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3920169/ https://ncbi.nlm.nih.gov/pubmed/24520212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.7727 |
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