Normal cardiac function in mice with supraphysiological cardiac creatine levels

Creatine and phosphocreatine levels are decreased in heart failure, and reductions in myocellular phosphocreatine levels predict the severity of the disease and portend adverse outcomes. Previous studies of transgenic mouse models with increased creatine content higher than two times baseline showed...

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Detalhes bibliográficos
Main Authors: Santacruz, Lucia, Hernandez, Alejandro, Nienaber, Jeffrey, Mishra, Rajashree, Pinilla, Miguel, Burchette, James, Mao, Lan, Rockman, Howard A., Jacobs, Danny O.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Energetics and Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920135/
https://ncbi.nlm.nih.gov/pubmed/24271489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00411.2013
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