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Normal cardiac function in mice with supraphysiological cardiac creatine levels

Creatine and phosphocreatine levels are decreased in heart failure, and reductions in myocellular phosphocreatine levels predict the severity of the disease and portend adverse outcomes. Previous studies of transgenic mouse models with increased creatine content higher than two times baseline showed...

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Главные авторы: Santacruz, Lucia, Hernandez, Alejandro, Nienaber, Jeffrey, Mishra, Rajashree, Pinilla, Miguel, Burchette, James, Mao, Lan, Rockman, Howard A., Jacobs, Danny O.
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920135/
https://ncbi.nlm.nih.gov/pubmed/24271489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00411.2013
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