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ENaC activity is increased in isolated, split-open cortical collecting ducts from protein kinase Cα knockout mice
The epithelial Na channel (ENaC) is negatively regulated by protein kinase C (PKC) as shown using PKC activators in a cell culture model. To determine whether PKCα influences ENaC activity in vivo, we examined the regulation of ENaC in renal tubules from PKCα(−/−) mice. Cortical collecting ducts wer...
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Huvudupphovsmän: | , , , , , , , , |
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Materialtyp: | Artigo |
Språk: | Inglês |
Publicerad: |
American Physiological Society
2013
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Ämnen: | |
Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3920049/ https://ncbi.nlm.nih.gov/pubmed/24338818 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00519.2013 |
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