Activation of Signaling Pathways Following Localized Delivery of Systemically-Administered Neurotrophic Factors across the Blood-Brain Barrier Using Focused Ultrasound and Microbubbles

The brain-derived neurotrophic factor (BDNF) has been shown to have broad neuroprotective effects in addition to its therapeutic role in neurodegenerative disease. In this study, the efficacy of delivering exogenous BDNF to the left hippocampus is demonstrated in wild-type mice (n=7) through the non...

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Hlavní autoři: Baseri, Babak, Choi, James J., Deffieux, Thomas, Samiotaki, Mania, Tung, Yao-Sheng, Olumolade, Oluyemi, Small, Scott A., Morrison, Barclay, Konofagou, Elisa E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3919955/
https://ncbi.nlm.nih.gov/pubmed/22407323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/0031-9155/57/7/N65
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