DNA methylation and regulation of the human beta-globin-like genes in mouse erythroleukemia cells containing human chromosome 11.

The human beta-globin gene is expressed--but the human fetal (gamma) and embryonic (epsilon) globin genes are not--in an induced mouse erythroleukemia cell line (M11-X) that contains most of human chromosome 11. A 24-hr exposure of M11-X cells to 5-azacytidine before induction causes "global&qu...

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Bibliographic Details
Main Authors: Ley, T J, Chiang, Y L, Haidaris, D, Anagnou, N P, Wilson, V L, Anderson, W F
Format: Artigo
Language:Inglês
Published: 1984
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC391981/
https://ncbi.nlm.nih.gov/pubmed/6208553
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