DNA methylation and regulation of the human beta-globin-like genes in mouse erythroleukemia cells containing human chromosome 11.

The human beta-globin gene is expressed--but the human fetal (gamma) and embryonic (epsilon) globin genes are not--in an induced mouse erythroleukemia cell line (M11-X) that contains most of human chromosome 11. A 24-hr exposure of M11-X cells to 5-azacytidine before induction causes "global" DNA hy...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Ley, T J, Chiang, Y L, Haidaris, D, Anagnou, N P, Wilson, V L, Anderson, W F
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1984
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391981/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6208553/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.21.6618
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