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Comparative kinetic analyses of gene profiles of naïve CD4(+) and CD8(+) T cells from young and old animals reveal novel age-related alterations

It is well established that immune responses are diminished in the old. However, we still do not have a clear understanding of what dictates the dysfunction of old T cells at the molecular level. Although microarray analysis has been used to compare young and old T cells, identifying hundreds of gen...

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Bibliografiske detaljer
Main Authors: Mirza, Noweeda, Pollock, Kevin, Hoelzinger, Dominique B., Dominguez, Ana Lucia, Lustgarten, Joseph
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3919687/
https://ncbi.nlm.nih.gov/pubmed/21711441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2011.00730.x
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