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Foxp3-positive macrophages display immunosuppressive properties and promote tumor growth

Regulatory T cells (T reg cells) are characterized by the expression of the forkhead lineage-specific transcription factor Foxp3, and their main function is to suppress T cells. While evaluating T reg cells, we identified a population of Foxp3-positive cells that were CD11b(+)F4/80(+)CD68(+), indica...

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Main Authors: Zorro Manrique, Soraya, Duque Correa, Maria Adelaida, Hoelzinger, Dominique B., Dominguez, Ana Lucia, Mirza, Noweeda, Lin, Hsi-Hsien, Stein-Streilein, Joan, Gordon, Siamon, Lustgarten, Joseph
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135357/
https://ncbi.nlm.nih.gov/pubmed/21670203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20100730
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