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B7-H1 Expression on Old CD8(+) T Cells Negatively Regulates the Activation of Immune Responses in Aged Animals

T cell responses are compromised in the elderly. The B7-CD28 family receptors are critical in the regulation of immune responses. We evaluated whether the B7-family and CD28-family receptors were differentially expressed in dendritic cells, macrophages, and CD4(+) and CD8(+) T cells from young and o...

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Detalhes bibliográficos
Main Authors: Mirza, Noweeda, Duque, Maria Adelaida, Dominguez, Ana Lucia, Schrum, Adam G., Dong, Haidong, Lustgarten, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3919800/
https://ncbi.nlm.nih.gov/pubmed/20375308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903561
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