Neurotoxic effects of the HCV core protein are mediated by sustained activation of ERK via TLR2 signaling

Hepatitis C virus (HCV) infection is a serious problem among those co-infected with human immunodeficiency virus; however, its impact in the central nervous system (CNS) remains unclear. This study aimed to investigate the mechanisms underlying HCV core protein-mediated neurodegeneration. Analysis o...

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Autori principali: Paulino, Amy D., Ubhi, Kiren, Rockenstein, Edward, Adame, Anthony, Crews, Leslie, Letendre, Scott, Ellis, Ronald, Everall, Ian P., Grant, Igor, Masliah, Eliezer
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3919659/
https://ncbi.nlm.nih.gov/pubmed/21660601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13365-011-0039-0
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