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Prospective identification of parasitic sequences in phage display screens

Phage display empowered the development of proteins with new function and ligands for clinically relevant targets. In this report, we use next-generation sequencing to analyze phage-displayed libraries and uncover a strong bias induced by amplification preferences of phage in bacteria. This bias fav...

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Autori principali: Matochko, Wadim L., Cory Li, S., Tang, Sindy K.Y., Derda, Ratmir
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3919620/
https://ncbi.nlm.nih.gov/pubmed/24217917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1104
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