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Prospective identification of parasitic sequences in phage display screens

Phage display empowered the development of proteins with new function and ligands for clinically relevant targets. In this report, we use next-generation sequencing to analyze phage-displayed libraries and uncover a strong bias induced by amplification preferences of phage in bacteria. This bias fav...

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Detalles Bibliográficos
Main Authors: Matochko, Wadim L., Cory Li, S., Tang, Sindy K.Y., Derda, Ratmir
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3919620/
https://ncbi.nlm.nih.gov/pubmed/24217917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1104
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