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Phage Display of the Serpin Alpha-1 Proteinase Inhibitor Randomized at Consecutive Residues in the Reactive Centre Loop and Biopanned with or without Thrombin

In spite of the power of phage display technology to identify variant proteins with novel properties in large libraries, it has only been previously applied to one member of the serpin superfamily. Here we describe phage display of human alpha-1 proteinase inhibitor (API) in a T7 bacteriophage syste...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Scott, Benjamin M., Matochko, Wadim L., Gierczak, Richard F., Bhakta, Varsha, Derda, Ratmir, Sheffield, William P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3888415/
https://ncbi.nlm.nih.gov/pubmed/24427287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084491
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