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Cycling of the E. coli lagging strand polymerase is triggered exclusively by the availability of a new primer at the replication fork

Two models have been proposed for triggering release of the lagging strand polymerase at the replication fork, enabling cycling to the primer for the next Okazaki fragment—either collision with the 5′-end of the preceding fragment (collision model) or synthesis of a new primer by primase (signaling...

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Dettagli Bibliografici
Autori principali: Yuan, Quan, McHenry, Charles S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3919610/
https://ncbi.nlm.nih.gov/pubmed/24234450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1098
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