Life without tRNA(Ile)-lysidine synthetase: translation of the isoleucine codon AUA in Bacillus subtilis lacking the canonical tRNA(2)(Ile)

Translation of the isoleucine codon AUA in most prokaryotes requires a modified C (lysidine or agmatidine) at the wobble position of tRNA(2)(Ile) to base pair specifically with the A of the AUA codon but not with the G of AUG. Recently, a Bacillus subtilis strain was isolated in which the essential...

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Detalhes bibliográficos
Main Authors: Köhrer, Caroline, Mandal, Debabrata, Gaston, Kirk W., Grosjean, Henri, Limbach, Patrick A., RajBhandary, Uttam L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3919564/
https://ncbi.nlm.nih.gov/pubmed/24194599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1009
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