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The Catalytic Flexibility of tRNA(Ile)-lysidine Synthetase Can Generate Alternative tRNA Substrates for Isoleucyl-tRNA Synthetase

Bacteria decode the isoleucine codon AUA using a tRNA species that is posttranscriptionally modified at the wobble position of the anticodon with a lysine-containing cytidine derivative called lysidine. The lysidine modification of tRNA(Ile2) is an essential identity determinant for proper aminoacyl...

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Detalhes bibliográficos
Main Authors: Salowe, Scott P., Wiltsie, Judyann, Hawkins, Julio C., Sonatore, Lisa M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665086/
https://ncbi.nlm.nih.gov/pubmed/19233850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M809013200
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