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Experimental Traumatic Brain Injury Induces Rapid Aggregation and Oligomerization of Amyloid-Beta in an Alzheimer's Disease Mouse Model

Soluble amyloid-beta (Aβ) oligomers are hypothesized to be the pathogenic species in Alzheimer's disease (AD), and increased levels of oligomers in the brain subsequent to traumatic brain injury (TBI) may exacerbate secondary injury pathways and underlie increased risk of developing AD in later...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Washington, Patricia M., Morffy, Nicholas, Parsadanian, Maia, Zapple, David N., Burns, Mark P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3919479/
https://ncbi.nlm.nih.gov/pubmed/24050316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2013.3017
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