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Amyloid-beta Oligomerization in Alzheimer Dementia vs. High Pathology Controls
OBJECTIVE: While amyloid-beta (Aβ) peptide deposition into insoluble plaques is a pathological hallmark of Alzheimer’s disease, soluble oligomeric Aβ has been hypothesized to more directly underlie impaired learning and memory in dementia of the Alzheimer type. However, the lack of a sensitive, spec...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3563737/ https://ncbi.nlm.nih.gov/pubmed/23225543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.23748 |
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