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Soluble amyloid-beta buffering by plaques in Alzheimer disease dementia versus high-pathology controls

An unanswered question regarding Alzheimer disease dementia (ADD) is whether amyloid-beta (Aβ) plaques sequester toxic soluble Aβ species early during pathological progression. We previously reported that the concentration of soluble Aβ aggregates from patients with mild dementia was higher than sol...

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Veröffentlicht in:PLoS One
Hauptverfasser: Esparza, Thomas J., Gangolli, Mihika, Cairns, Nigel J., Brody, David L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6034844/
https://ncbi.nlm.nih.gov/pubmed/29979775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0200251
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