A mutant murine leukemia virus with a single missense codon in pol is defective in a function affecting integration.
We have used site-directed mutagenesis of cloned Moloney murine leukemia virus (MuLV) DNA to define a function encoded in the 3' region of the viral pol gene and required for efficient integration of viral DNA. One mutant, MuLV-SF1, contained a single base substitution (C to T at base 4950) that res...
Guardat en:
| Publicat a: | Proc Natl Acad Sci U S A |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1984
|
| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391944/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6208550/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.20.6461 |
| Etiquetes: |
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|