Regulation of IL-4 Receptor Signaling by STUB1 in Lung Inflammation

Rationale: IL-4Rα, the common receptor component for IL-4 and IL-13, plays a critical role in IL-4– and IL-13–mediated signaling pathways that regulate airway inflammation and remodeling. However, the regulatory mechanisms underlying IL-4Rα turnover and its signal termination remain elusive. Objecti...

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Detalhes bibliográficos
Main Authors: Wei, Qin, Sha, Youbao, Bhattacharya, Abhisek, Fattah, Elmoataz Abdel, Bonilla, Diana, Jyothula, Soma S. S. K., Pandit, Lavannya, Khurana Hershey, Gurjit K., Eissa, N. Tony
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3919125/
https://ncbi.nlm.nih.gov/pubmed/24251647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201305-0874OC
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